Motility Medications
Unfortunately, medications to treat chronic intestinal pseudo-obstruction are limited. Most of them are used to treat symptoms and not the underlying disorder which limits effectiveness.
Aciphex- Used for GERD
Ativan - used to control nausea, but causes extreme drowsiness
Bethanechol - Used to stimulate esophageal motility
Compazine- Used to control nausea, but can cause drowsiness, restlessness, etc.
Domperidone- Not FDA approved, but still available at compounding pharmacies in the US, or in other countries.
www.inhousepharmacy.com
www.millerspharmacy.com,
1-888-891-3334
Erythromycin- Often used for motility, but typically is not very effective especially if taken with no other nausea meds. It may cause a prolonged QT interval on the EKG which can lead to sudden cardiac arrest, especially when used in conjunction with certain other medications.
Marinol- Approved Marijuana drug that is given to chemo patients or others with severe nausea
Nexium- Used for GERD as well as healing esophagus due to acid
Periactin (cyproheptadine)- Used to relax pyloric sphincter and as appetite stimulant
Phenergan- Used for nausea, but can cause drowsiness and restlessness.
Prevacid, Prilosec- Used for GERD
Reglan- Used for nausea relief and to increase motility. Unfortunately, it is not very well tolerated by many patients.
Tricyclic Antidepressants (Elavil, nortriptyline, etc)- in small doses these help with nausea.
Zelnorm- Used for abdominal pain or discomfort, bloating, and constipation. Zelnorm was removed from the market in 2005.
Zofran- Used in chemo patients for nausea.
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